This course provides a comprehensive introduction to unmanned aerial vehicle systems, including their fundamental components, operating principles, and practical applications. Topics include UAV classifications, flight principles, propulsion systems, sensors, navigation and positioning, wireless communications, flight control systems, ground control station software, mission planning, flight safety, and outdoor flight operation. The course also introduces UAV regulations, airspace restrictions, cybersecurity, privacy, autonomous flight technologies, and artificial intelligence applications. Students will learn the fundamentals and practical implementation of CNNs, Transformers, YOLO object detection, and large language models for UAV-related tasks. Through lectures, demonstrations, hands-on exercises, model training, and team-based projects, students will develop the knowledge and practical skills required to operate, configure, integrate, and apply UAV systems in real-world scenarios.