After completing this course you should understand fundamental concepts of CDSS, have capabilities to make a good presentation. The major goal of the first stage of this course is to teach fundamental concepts of decision-making in healthcare and Clinical Decision Support Systems (CDSS). The scope of the course will cover all materials delivered in our lectures and assigned readings. The goal of the second stage is to introduce several real CDSS cases available in healthcare market. You are asked to collect relevant paper and make a presentation.