(I) Course Description–(3 credits):
This course provides a comprehensive exploration of organotransition metal chemistry, with a focus on reaction mechanisms, structure-reactivity relationships, and applications in catalysis and organic synthesis. We will begin with the fundamentals of bonding and structure, including the 18-electron rule, and progress to advanced topics such as ligand substitution, oxidative addition, reductive elimination, insertion/elimination reactions, and the role of carbenes in catalysis. Modern characterization techniques for organometallic compounds will be covered. The course will culminate in an examination of catalytic applications of organometallic complexes, including industrial processes and the activation of small molecules.
(II) Objectives:
Upon successful completion of this course, students will be able to:
★ Master fundamental principles: Demonstrate a deep understanding of the principles governing the structure, bonding, and reactivity of organotransition metal compounds.
★ Analyze structure and bonding: Apply knowledge of bonding models (including the 18-electron rule) to predict the stability and reactivity of organometallic complexes.
★ Evaluate characterization methods: Critically evaluate and interpret data from modern characterization techniques used in organometallic chemistry.
★ Understand reaction mechanisms: Describe and explain key organometallic reaction mechanisms, including ligand substitution, oxidative addition, reductive elimination, insertion/elimination reactions, and carbene-mediated reactions.
★ Apply knowledge to catalysis: Apply their understanding of organometallic chemistry to analyze and design catalytic processes, including those relevant to industrial applications and small molecule activation.
★ Communicate effectively in English: Confidently use English to discuss, read, and write about complex topics in organometallic chemistry.